In a double-blind study, EN Schachter and A Schlesinger investigated
the role of ascorbic acid in exercise-induced bronchospasm in asthmatics. They found
pretreatment with ascorbic acid led to a significant attenuation of the bronchospasm seen
five minutes after exercise compared to placebo as measured by FVC (.24 vs .48). and by
FEV1 (.24 decrease vs .44 decrease after placebo).55
This study was supported by evidence presented by M Miric and MA
Haxhiu, in 1991. The effect of vitamin C on exercise-induced airway constriction
was studied. Pretreatment with ascorbic acid prevented the significant alteration in
airway geometry induced by exercise in asthmatic patients. These results suggest that
vitamin C deficiency might augment airway responses to exercise and other
bronchospasmogenic factors, and treatment with vitamin C may decrease airway
hyperresponsiveness.56
I Neuman, et al. showed that a daily
dose of beta carotene exerted a protective effect against exercise-induced asthma in 53%
of patients after only one week.57 |